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StoneWise

ChinaDrug discoveryBeijing, ChinaFounded 2018Private

Website · stonewise.cn ↗

AI small-molecule design software and molecule-generation models with its own chemistry lab, sold to drugmakers; its AI-assisted HPK1 inhibitor SWA1211 is cleared for trials.

Disclosed total$100M
Rounds on record4
Latest round$100MSeries B and B+ · 2021-04-12
Last stated valuationNone stated
Investors named9
Research on record1highest level 3 · Checked against existing evidence

Money and evidence

Moneyeach round in US dollars; ≈ converted at its date20192020202120222023202420252026AngelSeries AA+$100MEvidencelevel of each research entry12345
Closed roundNot on the dollar scale (a range, or no rate)Research entry, at its level

Latest round, Series B and B+, 2021-04-12: the record then held no research entry for the company. The first research entry is dated 2026-02-07; the highest level so far is 3 (Checked against existing evidence).

Rounds and research, on one timeline

  1. 2026-02-07
    Research

    Level 3 · Checked against existing evidence

    StoneWise publishes HEAD, an open-source tool that flags implausible atoms and over-strained bonds in AI-generated 3D molecules at near-quantum accuracy

    As generative models pour out candidate 3D molecules, telling a physically sensible one from a distorted one is the bottleneck, and the usual checks are either fast-but-crude geometry rules or slow, inaccurate mechanics energies. HEAD aims for quantum-chemistry-level judgement at a speed that can screen large batches, and it separates two faults a single score blurs together: an atom sitting in an impossible spot, and a bond twisted into a high-energy pose. Being open source, it lets other groups hold generated molecules to the same bar.

    Timeline entry →nature.com ↗

  2. 2021-04-12Series B and B+
    Round

    $100M

    For: talent, platform deployment, faster iteration

    HiringModels and platform

    $100M is the two rounds combined.

    Co-lead · Legend Capital (B)Co-lead · Lightspeed China (B+)Co-lead · Greater Bay Area Homeland Development Fund (B+)CDH VGC ✓Zhongding CapitalGL VenturesSIGChangling CapitalLinear Capital ✓

    On the deal: Jiaqing Li (President, Legend Capital (B)); Mingyu Wang (Senior Partner, CDH VGC); Yan Han (Founding Partner, Lightspeed China (B+))

    The investor's own page says · Linear Capital: 2020

    Announced by the company · vbdata.cn ↗

  3. 2020-09-09A+
    Round

    several million US dollars

    For: AI drug-discovery platform, team, partnerships

    Models and platformHiringCommercial roll-out

    Lead · GL VenturesLinear Capital (over-allocated) ✓

    On the deal: Liming Huang (Hillhouse partner, head of software & hard tech at GL Ventures, GL Ventures)

    Announced by the company · vbdata.cn ↗

  4. 2020-03-16Series A
    Round

    nearly US$10 million

    For: platform, core products, data, partnerships, hiring

    Models and platformData generationCommercial roll-out

    PEdaily report reposted on OFweek.

    Co-lead · Changling CapitalCo-lead · Linear Capital ✓

    Announced by the company · mp.ofweek.com ↗

  5. 2018-12Angel
    Round

    amount not disclosed

    Not stated

    Known only from the A+ announcement's round history ('end of 2018').

    Lead · SIG

    Announced by the company · vbdata.cn ↗

Research entries are the timeline's graded entries that name this company. A level grades one claim, not the company, and a blank can mean the record has not caught up rather than that nothing was published.

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On the investors' own sites

Investors that name this company on their own site, in a portfolio or their own announcement. A ✓ in a round marks the same investor.

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