Peyton Greenside
Researcher · Founder
Now Founder, BigHat Biosciences
Latest on AI4S.fyiTimeline · Oct 27BigHat and Anthropic improve two antibody leads over seven rounds, after finding one thermal measure did not measure what its name saidAccount confirmed by the editor · Avatar from their X account, taken 2026-09-28
Affiliations
Current
- Founder · BigHat Biosciences
Also named in the companies' announcements: Stanford
Current roles come from these dated records, not from the bio below. Each links the page it was read from.
About
Peyton Greenside is co-founder and chief executive of BigHat Biosciences, which combines machine learning and synthetic biology to design antibody therapeutics; she moved from chief scientific officer to CEO in 2025. She was an inaugural Schmidt Science Fellow and a computational biologist at the Broad Institute. She holds a doctorate in biomedical informatics from Stanford, an MPhil from Cambridge as a Herchel Smith scholar, and a BA from Harvard.
Read on 2026-09-29; for current roles see Affiliations above. Read at: biospace.com ↗ · bighatbio.com ↗
Selected work
- Bayesian Optimization of Antibodies Informed by a Generative Model of Evolving Sequences (CloneBO) ↗
Optimizes antibodies with a generative model trained on how antibody sequences evolve in the immune system.
- Accelerating Bayesian Optimization for Biological Sequence Design with Denoising Autoencoders (LaMBO) ↗
Bayesian optimization for designing biological sequences, searching with a denoising autoencoder.
- Learning Important Features Through Propagating Activation Differences (DeepLIFT) ↗
A method that attributes a neural network's prediction to its input features.
Each byline was read on the paper itself. Only people on this record are named, not the full author list, and a shared byline does not say who did which part.
Founded
BigHat BiosciencesProtein design · 2019 · 3 rounds on record · disclosed $169M · Series C $75MBackground: Stanford (biomedical informatics PhD) (as the company's own announcements put it)
Co-founders: Mark DePristo
Backed byDFJ GrowthPremji InvestSection 32Andreessen Horowitz
On the timeline
Something wrong or missing on this page? Tell me and it will be fixed or removed. Contact →