Lab to Company · LAB TO COMPANY 005 · A large company spins out a team
Anew Labs: ByteDance's AI drug-discovery team becomes its own company, raising $290M from outside
The question · When a large company turns an internal team into a separate company, which models, code and labs go with it, and which stay behind?
At a glance · A first outside round of $290M (media-reported); ByteDance reportedly keeps 56%; announcements of the spin-out or the round by ByteDance, Anew or any investor: none.
One of the Lab to Company series. Each piece reads the public record through five roles: who supplies the research (the results, methods or team it came from), who holds the IP (patents, licences, what a parent kept), who gives the lab and equipment, who puts in the first money and on what terms, and who joins the company. It records only what the public record states and says who said each thing; a missing step is marked not yet public, and a company's own figure is written as the company's.
Anew Labs was ByteDance's AI drug-discovery team, set up in 2021 under Kai Liu, building protein structure, affinity and design models and its own antibody, small-molecule and peptide programmes.[1][3] From June 2026 outlets reported it was being spun out, and on 16 September that it had closed a first outside round of $290M at about $1.5B after the money, led by HSG (formerly Sequoia China), IDG Capital and Hillhouse.[1][2][3] Neither ByteDance nor Anew has announced the spin-out or the round on its own channels; every capital figure below comes from outlets, most citing unnamed people.
Who supplies the research · ByteDance. The team's public models all came out of ByteDance: the Protenix structure model was released in January 2025 under "ByteDance AML AI4Science Team", and its v1 and v2 under ByteDance Seed.[4] Anew's site now presents Protenix, SeedFold and its own AnewFold as one suite.[6] Several Anew papers in early 2026 carry both "ByteDance AI Drug Discovery" and a Singapore entity, Anew Therapeutics, with co-authors from Tsinghua University's Institute for AI Industry Research and others.[5] The leads of two of those models did not come along: outlets report that Wenzhi Xiao (Protenix) and Quanquan Gu (SeedFold) left to found companies before the spin-out.[9][10]
Who holds the IP · The assets moved; how is not yet public. 36Kr's Intelligent Emergence column reported that the core team, algorithms, platform and existing pipeline would "enter the new entity as a whole", with ByteDance keeping control.[1] Yet the model code still sits under ByteDance's GitHub with ByteDance copyright marks; Protenix's code and earlier weights are open under Apache 2.0, while the v2 weights belong to an unnamed "rights holder" and are not open.[4] Whether the move was an assignment, a licence or assets exchanged for equity is not public.
Who gives the lab and equipment · Compute comes from ByteDance's Volcano Engine, on terms not stated.[1][2] The company's site lists addresses in Shanghai, Singapore and the US.[6] Where wet-lab work is done is not stated: the careers page asks the head of medicinal chemistry to manage "the internal medicinal chemistry team and external CROs", and the technical report's antibody expression and binding tests do not say who ran them.[7][8]
Who puts in the first money, and on what terms · As reported: $290M, led by HSG, IDG Capital and Hillhouse, with 5Y Capital as co-lead and Gaorong, Primavera, Boyu, the Shanghai Future Industry Fund and Sino Biopharmaceutical (strategic) taking part.[2][3][13] Reuters, citing two unnamed people, says ByteDance keeps 56%; whether it put in new cash is not public.[2] The only investor speaking on the record is Sino Biopharm's Cao Fenze, who says the company wants to work with technology companies including ByteDance to bring frontier technology into real drug pipelines.[11] Kai Liu spent seven years in venture capital at IDG Capital and Fire Stone before ByteDance; IDG is one of this round's leads.[2]
Who joins the company · The team moved over as a whole, about 50 core members per outlets.[1][3] Kai Liu leads it.[6][8] In May 2026 the site listed 36 core members and three scientific advisers, among them Liu Yongjun, a former president of Innovent Biologics; the current site has taken the list down.[12] In June the structure-prediction team was merged into Kai Liu's drug team and "a few people left".[1]
What each side put in
- ByteDance put in the team, five years of research, an existing pipeline and compute, and reportedly keeps a majority stake; the copyright marks on the models are still its own.[1][2][4]
- The outside investors put in $290M and joined a team that already has models and a pipeline, rather than a project starting from nothing.[2][3]
- A drugmaker, Sino Biopharmaceutical, came in as a strategic investor, with the stated aim of bringing the technology into real drug pipelines.[11]
Not yet public · Any official announcement or filing on the spin-out or the round; whether the assets were assigned, licensed or swapped for equity; who owns the Protenix v2 weights; whether ByteDance put in new money, the board and the share terms; whether wet-lab work is in-house or outsourced; the current team list.
Decision point · The next thing to watch is whether the rights to Protenix and the other models move into Anew's name, a decision between ByteDance and Anew. Until then, what the company owns can only be read from outlets' unnamed sources.[1][4]
The chain's timeline
- 2021ByteDance's AI drug-discovery team set up under Kai Liu[1][3]
- 2025-01Protenix released under ByteDance's name, Apache 2.0[4]
- 2026-02 to 03Papers start carrying "Anew Therapeutics, Singapore"[5]
- 2026-04Protenix v2, weights not open[4]
- 2026-06Outlets report the spin-out; Wenzhi Xiao and Quanquan Gu have left[1][9]
- 2026-09-16Outlets report the $290M first outside round at about $1.5B[2][3]
- NextAn official announcement from any party; the transfer of model rights. Awaiting public data.
- LaterThe first programme into the clinic.
Sources
- 36Kr's Intelligent Emergence column, Zhou Xinyu, 2026-06-10. 36kr.com ↗ (read in full)
- The Next Web (relaying Reuters), 2026-09-16. thenextweb.com ↗ (read in full; the Reuters original could not be opened)
- Yicai, Lyu Qian, 2026-09-16. yicai.com ↗ (read in full)
- Protenix repository README and licence. github.com ↗ (README and LICENSE read)
- AnewOmni, bioRxiv, 2026-03. doi.org ↗ (authors and affiliations read)
- Anew Labs website. anewbt.com ↗ (read)
- Anew Labs careers page. anewbt.com ↗ (read)
- AnewDDE technical report, 2026-09. anewlabs-research.tos-cn-beijing.volces.com ↗ (read by section)
- STAR Market Daily, Wang Nai, 2026-06-11. cls.cn ↗ (read in full)
- VCBeat (36Kr English edition), 2026-09-17. eu.36kr.com ↗ (first half read)
- The Economic Observer (36Kr English edition), 2026-10-12. eu.36kr.com ↗ (first half read)
- The Next Web (relaying the South China Morning Post), 2026-05-02. thenextweb.com ↗ (most read)
- PEdaily's first report (Gelonghui's copy), 2026-09-16. m.gelonghui.com ↗ (read in full)

