

Polyphron
Grows human micro-tissues from donor-diverse stem cells in an automated foundry, measures how they respond over time, and trains a tissue model on that data, to test AI-generated drug hypotheses; cardiac tissue first, liver next.
Money and evidence
Latest round, Seed, 2026-09-17: the record then held 1 research entry, highest level 4. The first research entry is dated 2026-04-07; the highest level so far is 4 (Tested in the physical world).
Rounds and research, on one timeline
- 2026-09-17SeedRound
$20M
For: building its tissue platform as it expands its tissue models and AI capabilities
Wet labModels and platform
CEO Matthew Osman names the amount and investors in AlleyWatch's interview; the use comes from HLTH's summary of the company's Business Wire release of 17 September, which returned 403 here. Osman also lists six-month goals: more cardiac and liver data, more automation and a donor panel of over 20 lines.
Lead · Quiet CapitalHaystackGradientCompound
By this date the record held 1 research entry, highest level 4
Announced by the company · alleywatch.com ↗On the timeline →
- 2026-04-07Research
Level 4 · Tested in the physical world
Polyphron and Cellino grow aligned brain tissue from four donors' stem cells, predicting the conditions for two thinly tested donors from the other two
Stem cells from different people respond differently to the same recipe, which is a main reason grown human tissue does not scale. Here the foundry carried what it learned on two donors over to two others with little data, the step a bank of patient-matched tissue would need.
Research entries are the timeline's graded entries that name this company. A level grades one claim, not the company, and a blank can mean the record has not caught up rather than that nothing was published.
Its investors also backed
Other companies on this page whose rounds name the same investor.
- CompoundAchira, Orbital Industries
- Quiet CapitalBiossil
- HaystackOnyx Bio