


Insilico Medicine
Also known as InSilico Medicine
Generative-AI drug discovery (target finding, molecule generation) with its own clinical pipeline led by a fibrosis drug, plus licensing deals with Lilly, Exelixis and others.
Listed on the Hong Kong main board on 2025-12-30 (3696.HK) at HK$24.05 per share; over-allotment fully exercised on 2026-01-16.
Money and evidence
Latest round, IPO, 2025-12-30: the record then held 1 research entry, highest level 5. The first research entry is dated 2025-06-03; the highest level so far is 5 (Used in practice).
Rounds and research, on one timeline
- 2026-09-17Research
Level 2 · Computed
Insilico and collaborators publish a 17-task benchmark and specialist LLMs for aging biology
Aging has no agreed definition, unlike cancer's crisp endpoints, so the benchmark's contribution is turning that ambiguity into 17 checkable tasks rather than one contested clock.
- 2026-09-07Research
Level 3 · Checked against existing evidence
Insilico ran six proteomic aging clocks on blood from its rentosertib trial, and treated patients read biologically younger than placebo, most clearly at week four
It is an attempt to read an aging endpoint out of a disease trial, which is the trial design Insilico is arguing for. But it is the sponsor's exploratory reanalysis of stored samples, with nine to eleven patients per arm at each time point and seven Insilico employees among the authors. The authors say proteomic clocks alone cannot separate slower aging from a treated disease, that they could only address this indirectly, and that doing it properly needs healthy volunteers. The readings did not move further between weeks four and twelve.
- 2025-12-30IPORound
about HK$2.026B net≈ $260M
For: late-stage clinical programmes, new generative AI models, automated labs and early discovery
Toward the clinicModels and platformAutomated lab
94,690,500 shares at HK$24.05. Net figure from the allotment announcement as relayed by Gelonghui; the over-allotment added about HK$324.5M net on 2026-01-16. Use of proceeds from The Paper's report of the May 2025 prospectus filing; the final prospectus was not read. The 15 cornerstone investors are from 36Kr's report at the offer launch, drawn from the prospectus (https://www.36kr.com/p/3600333723058178).
Anchor · LillyAnchor · TencentAnchor · TemasekAnchor · OaktreeAnchor · SchrodersAnchor · UBSAnchor · ChinaAMCAnchor · China Pacific Insurance (CPIC)Anchor · Fullgoal Fund ManagementAnchor · Harvest Fund ManagementAnchor · Taikang LifeAnchor · E Fund ManagementAnchor · RTWAnchor · ExomeAnchor · Infini
By this date the record held 1 research entry, highest level 5
- 2025-06-03Research
Level 5 · Used in practice
An AI-discovered drug reaches randomized Phase 2a evidence
Once an AI-discovered molecule reaches controlled human trials, clinical safety and efficacy become more important evidence than the sophistication of the discovery model.
- 2025-03-13Series ERound
$110M
For: AI models, automated lab, clinical validation of the lead IPF drug
Models and platformAutomated labToward the clinic
Last private round before the IPO.
Lead · Value Partners Group private equity fund
On the deal: Chuen Yan Leung (Partner, Value Partners Group private equity fund)
- 2022-08-10Series D (second close)Round
$35M
For: accelerate internal programmes and use its AI platform to find more new therapeutics
Models and platform
Brings Series D to $95M in aggregate.
- 2022-06-06Series DRound
$60M
For: pipeline, Pharma.AI, robotic drug-discovery lab
Models and platformAutomated lab
No lead named; the founder invested personally.
BHR PartnersWarburg Pincus ✓B Capital Group ✓Qiming Venture Partners ✓BOLD Capital PartnersPavilion CapitalAlex Zhavoronkov
On the deal: Min Fang (Managing Director, Head of China Healthcare, Warburg Pincus)
- 2021-06-22Series CRound
$255M
For: take programs into human trials; start new programs
Toward the clinic
Lead · Warburg Pincus ✓Qiming Venture Partners ✓Lilly Asia VenturesOrbiMed ✓Deerfield ManagementSequoia Capital China ✓B Capital Group ✓Pavilion CapitalEight Roads VenturesSinovation Ventures ✓BOLD Capital PartnersFormic VenturesBaidu Ventures ✓CPEMirae Asset CapitalMaison CapitalLake Bleu CapitalPresident International Development CorporationSage Partners
On the deal: Fred Hassan (Spoke for Warburg Pincus, Warburg Pincus); Min Fang (Managing Director, Warburg Pincus, joins the board)
The investor's own page says · Warburg Pincus: Investment Year 2021 (Stage: Growth)
- 2019-09-10Series BRound
$37M
For: commercialise its generative chemistry and target identification technology, build a senior team with pharma experience, and develop its pipeline in cancer, fibrosis, NASH, immunology and CNS for partnering
Commercial roll-outHiring
The release names Qiming Venture Partners as the lead; F-Prime Capital and Eight Roads participated. Series A investors also joined, unnamed.
Lead · Qiming Venture Partners ✓Eight Roads VenturesF-Prime Capital ✓Lilly Asia VenturesSinovation Ventures ✓Baidu Ventures ✓Pavilion CapitalBOLD Capital Partners
On the deal: Nisa Leung (Managing Partner, Qiming Venture Partners)
Research entries are the timeline's graded entries that name this company. A level grades one claim, not the company, and a blank can mean the record has not caught up rather than that nothing was published.
On the investors' own sites
Investors that name this company on their own site, in a portfolio or their own announcement. A ✓ in a round marks the same investor.
- B Capital Groupb.capital ↗
- Baidu Venturesbaidu-ventures.com ↗
- F-Prime2019 (from post URL only)fprimecapital.com ↗
- OrbiMedorbimed.com ↗
- Qiming Venture Partnersqimingvc.com ↗
- Sequoia Capital Chinahongshan.com ↗
- Sinovation Ventureschuangxin.com ↗
- Warburg PincusInvestment Year 2021 (Stage: Growth)warburgpincus.com ↗
Its investors also backed
Other companies on this page whose rounds name the same investor.
- HSG (Sequoia China)Anew Labs, MoleculeMind, METiS TechBio
- Qiming Venture PartnersBIOTREE, DP Technology, Aureka Biotechnologies
- TemasekIsomorphic Labs, CuspAI, Vinci
- Baidu VenturesMoleculeMind, DP Technology, Deep Principle
- F-PrimeXaira Therapeutics, Albert, Owkin
- DeerfieldRelation Therapeutics, METiS TechBio
- Eight Roads VenturesOwkin
- Lake BleuMETiS TechBio
- Mirae AssetMETiS TechBio
- OrbiMedIambic Therapeutics
- RTWMETiS TechBio
- Sage PartnersMETiS TechBio
- Fullgoal Fund ManagementMETiS TechBio